Cleanance Comedomed, an innovation from Laboratoires Eau Thermale Avène has shown proven clinical effectiveness from seven days*, fights blemishes from the root and prevents them from reappearing. Expert care for oily, blemish-prone skin, Cleanance Comedomed is formulated using Comedoclastin™, a plant extract from the seeds of milk thistle. This active ingredient with patented properties** reduces existing blemishes and blackheads, limits new ones appearing, and reduces excess sebum. Cleanance Comedomed is suitable for adults and teenagers from the age of 12, applied twice a day, morning and evening, and offers clinically-proven*** anti-recurrence action. Non-comedogenic, high-tolerance* for blemish-prone skin, its fast-absorbing, non-greasy texture leaves skin mattified.

*Tolerance and efficacy study under dermatological control on 51 subjects, use of Cleanance Comedomed twice a day for 56 days.
** Patent registered.
***International clinical observational study, 90% of individuals without blemish relapse at T6 months, (according to the definition of relapse in the GEA protocol ?3 requiring the introduction of a drug treatment – oral or local), 48 subjects, two applications per day of Cleanance Comedomed for six months.